Image cytometry has emerged as a valuable in vitro screening tool and advances in automated microscopy have made it possible to readily analyze large cellular populations of image data. The purpose… (More)
A Task Deliverable under a Collaboration between ITL's Statistical Engineering (898) and Software Diagnostics and Conformance Testing (897) Divisions to pursue Statistical Methods that may be… (More)
To evaluate the performance of fingerprint-image matching algorithms on large datasets, a receiver operating characteristic (ROC) curve is applied. From the operational perspective, the true accept… (More)
For many shape analysis problems in computer vision and scientific imaging (e.g., computational anatomy, morphological cytometry), the ability to align two closed curves in the plane is crucial. If… (More)
Software testing is hard, expensive, and uncertain. Many protocols have been suggested, especially in the area of conformance veri cation. In order to compare the e cacy of these protocols, we have… (More)
Effective computational tools for shape analysis are needed in many areas of science and engineering. We address this and propose a new fast iterative algorithm to compute the elastic geodesic… (More)
The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH), has developed a Standard Reference Material (SRM) to support technology… (More)
Curve registration problems in data analysis and computer vision can often be reduced to the problem of matching two functions defined on an interval. Dynamic Programming (DP) is an effective… (More)
Cell segmentation is a critical step in the analysis pipeline for most imaging cytometry experiments and evaluating the performance of segmentation algorithms is important for aiding the selection of… (More)