• Publications
  • Influence
Randomised trial of Haemophilus influenzae type-b tetanus protein conjugate vaccine [corrected] for prevention of pneumonia and meningitis in Gambian infants.
BACKGROUND In developing countries, pneumonia and meningitis due to Haemophilus influenzae type b (Hib) are common in children under age 12 months and the mortality from meningitis is high.Expand
  • 97
  • 7
Epidemiology of invasive pneumococcal disease in the Western Region, The Gambia.
BACKGROUND Streptococcus pneumoniae is a major cause of morbidity and mortality in young children in the developing world. The recent development of pneumococcal polysaccharide/protein conjugateExpand
  • 94
  • 3
Clinical predictors of hypoxaemia in Gambian children with acute lower respiratory tract infection: prospective cohort study
Abstract Objectives: To determine clinical correlates and outcome of hypoxaemia in children admitted to hospital with an acute lower respiratory tract infection. Design: Prospective cohort study.Expand
  • 75
  • 2
  • PDF
Clinical predictors of bacterial meningitis in infants and young children in The Gambia
Background  Bacterial meningitis is an important cause of childhood morbidity and mortality world‐wide. In the developing world, where the burden of acute meningitis and its long‐term sequelae areExpand
  • 31
  • 2
A randomized trial of chloramphenicol vs. trimethoprim‐sulfamethoxazole for the treatment of malnourished children with community‐acquired pneumonia
Children in developing countries who present with malnutrition often have infections, particularly pneumonia, at the time of presentation. We evaluated the initial antibiotic management of 144Expand
  • 22
  • 1
What's the use of Archimedes?
Last year, Archives of Disease in Childhood introduced a new section entitled “Archimedes”. Its purpose is “to assist practising clinicians by providing `evidence based' answers to common questionsExpand
  • 21
  • 1
  • PDF
Detection of Haemophilus influenzae and Streptococcus pneumoniae DNA in blood culture by a single PCR assay.
A multiplex PCR assay was developed to screen blood cultures from children in The Gambia with suspected pneumonia for the simultaneous detection of Haemophilus influenzae type b and StreptococcusExpand
  • 35
  • PDF
A polymerase chain reaction for the diagnosis of Haemophilus influenzae type b disease in children and its evaluation during a vaccine trial.
BACKGROUND Determination of the etiology of pneumonia in young children is difficult because blood culture, the usual method of diagnosis, is positive in only a small proportion of cases. For thisExpand
  • 15