Charles Meunier

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Understanding the complexity of the human brain and its functional diversity remain a major challenge. Distinct anatomical regions are involved in an array of processes, including organismal homeostasis, cognitive functions, and susceptibility to neurological pathologies, many of which define our species. Distal enhancers have emerged as key regulatory(More)
We have previously shown that the differential susceptibility of A/J (susceptible) and C57BL/6J (B6, resistant) mouse strains to azoxymethane (AOM)-induced colorectal cancer (CRC) is controlled by the chromosome 3 locus, Ccs3. We report that A/J and B6 mice also show differential susceptibility to colitis-associated colorectal cancer (CA-CRC) induced by(More)
We used a genome-wide screen in mutagenized mice to identify genes which inactivation protects against lethal neuroinflammation during experimental cerebral malaria (ECM). We identified an ECM-protective mutation in coiled-coil domain containing protein 88b (Ccdc88b), a poorly annotated gene that is found expressed specifically in spleen, bone marrow, lymph(More)
The Ccs3 locus on mouse chromosome 3 regulates differential susceptibility of A/J (A, susceptible) and C57BL/6J (B6, resistant) mouse strains to chemically-induced colorectal cancer (CRC). Here, we report the high-resolution positional mapping of the gene underlying the Ccs3 effect. Using phenotype/genotype correlation in a series of 33 AcB/BcA recombinant(More)
Modern field programmable gate array (FPGA) chips, with their larger memory capacity and reconfigurability potential, are opening new frontiers in rapid prototyping of embedded systems. With the advent of high-density FPGAs, it is now possible to implement a high-performance VLIW (very long instruction word) processor core in an FPGA. With VLIW(More)
Nous proposons dans cet article un outil de prototypage rapide des applications de traitement d'images sur des systèmes embarqués à base de FPGA. Le parallélisme intrinsèque au niveau des instructions a été automatiquement extrait à partir du code du source C (ou C++). Le modèle VHDL d'un processeur VLIW (Very Long Instruction Word) est généré et synthétisé(More)
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