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Journals and Conferences
The three-dimensional structures of indinavir and three newly synthesized indinavir analogs in complex with a multi-drug-resistant variant (L63P, V82T, I84V) of HIV-1 protease were determined to… (More)
We have developed a recombinant Escherichia coli screening system for the rapid detection and identification of amino acid substitutions in the human immunodeficiency virus (HIV) protease associated… (More)
Abstract D-malate esters were synthesized in one-pot from L-tartrate esters in 70-80% overall yields via the corresponding tartrate cyclic sulfites.
Abstract Asymmetric borane reduction of α-ketoimines with oxazaborolidine catalysts has been studied. The ee's of the resulting arylethanolamines are up to 93% using 20 mol% of the catalyst.
La presente invention concerne des composes et une composition associee et des procedes qui peuvent augmenter une reponse de type anticorps vis-a-vis de composes nicotiniques, dans certains modes de… (More)