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Selection and licensing of mammalian DNA replication origins may be regulated by epigenetic changes in chromatin structure. The Epstein-Barr virus (EBV) origin of plasmid replication (OriP) uses the cellular licensing machinery to regulate replication during latent infection of human cells. We found that the minimal replicator sequence of OriP, referred to(More)
We report MRI of the brain in 45 fetuses; the findings were confirmed by pathological examination or postnatal neuroradiological studies. MRI necessitates medication to eliminate fetal motion; curare was injected into the umbilical cord, and MRI is therefore limited to cases in which umbilical cord puncture is indicated. T1-weighted images were obtained in(More)
Introduction: Lymphomatosis cerebri is uncommon. It often poses a diagnostic challenge and carries a poor prognosis. Concurrent testicular lymphoma with lymphomatosis cerebri is even rarer. Case Report: A case of concurrent lymphomatosis cerebri and testicular lymphoma is presented. Gene arrangement studies helped to establish the diagnosis of lymphomatosis(More)
BACKGROUND Serum total human chorionic gonadotrophin β subunit (hCGβ) level might have prognostic value in urothelial transitional cell carcinoma (TCC) but has not been investigated for independence from other prognostic variables. METHODS We utilised a clinical database of patients receiving chemotherapy between 2005 and 2011 for urothelial TCC and an(More)
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