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Previous studies in rats have demonstrated that large lesions in the medial preoptic area (MPOA) disrupt all aspects of maternal behavior. In the present study, small bilateral electrolyte lesions in the MPOA of lactating females abolished nest building and retrieving components of maternal behavior while crouching and nursing were unaffected. Animals which(More)
In lactating female rats bilateral parasagittal cuts transecting the dorsolateral neural connections of the medial preoptic area (MPOA) abolished nest building and retrieving components of maternal behavior, while crouching and nursing were unaffected. While few animals with these cuts were suckled when presented with pups the prolactin secretion response(More)
The effects of depletion of hypothalamic norepinephrine (NE) during late pregnancy on the postpartum ovulatory LH surge, the onset and maintenance of maternal behavior and lactation were examined in adult female rats. Bilateral transections of the ascending noradrenergic pathways (ANP) between days 14 and 17 of gestation resulted in a 70% depletion in(More)
In freely-moving female rats the effects of intraventricular infusion of norepinephrine (NE) on multiunit activity (MUA) were examined in the Diagonal Band of Broca (DBB), medial preoptic area (MPOA) and anterior hypothalamic area (AHA), regions containing neurons producing luteinizing hormone-releasing hormone (LHRH). NE was infused at a dosage known to(More)
This study examined the alterations in episodic luteinizing hormone (LH) release in response to third ventricle infusions of various alpha- and beta-adrenoceptor agonists in ovariectomized (OVX) rats as well as the effects of steroid priming with 50 micrograms estradiol benzoate (EB) and 25 mg progesterone (P) on the LH responses to these agonists.(More)
Figure 14 summarizes some of the brain-pituitary-ovarian relationships which we have been discussing. Neurons in the arcuate nucleus of the hypophysiotropic area produce LRH which is secreted into the proximal capillary plexus of the hypophysio-portal system in the median eminence. LRH production is modulated in the rat and possibly also in the monkey by(More)