Charles Gerhardt

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The influence of intraduodenal bile deficiency due to chronic bile duct obstruction and acute exogenous administration of bile acids on plasma cholecystokinin (CCK) and pancreatic polypeptide (PP) was investigated. Fourteen patients with tumor-induced bile duct stenosis and five healthy volunteers were given a liquid test meal. Four of the patients had a(More)
Organic and inorganic nanoporous membranes, which are known to enhance the diffusion of certain species such as ions and to have a strong selectivity, are very attractive for nanofiltration and therapeutic applications. As a result, many experiments have been carried out to prepare and evaluate the performances of synthetic membranes that reproduce the(More)
The synthesis of amphiphilic lipid-polyoxazoline based on copolymers (CO-POx n) with narrow distribution has been achieved via cationic ring-opening polymerization of 2-methyl-2-oxazoline (MOx). Lipid-macroinitiator (COTs) was obtained from commercial castor oil (CO), widely renewable agricultural resource. CO-POx n with various length segments were(More)
Fluorinated hydroxytelechelic polybutadiene (PBF), synthesized from the radical addition of a fluorinated mercaptan onto a hydroxytelechelic polybutadiene was used as efficient surface and mechanical modifiers in original formulations to enable the UV cationic polymerization of a telechelic diepoxy cycloaliphatic resin, leading to crosslinked films. Various(More)
Fe 1-x O wüstite as negative electrode material for Li-ion batteries has been studied. The aim of this work is to get a better understanding of the insertion mechanism involved during reduction/oxidation processes. Electrochemical tests have been done in Swagelock TM cells and shown a high specific capacity of 800 Ah/kg for the first discharge. X-ray(More)
After simultaneous administration of dexamethasone together with 6-hydroxydopamine or adrenergic neuronal blocking agents (alpha-methyldopa, reserpine, guanethidine) the dexamethasone-stimulated increase in renal excretion of p-aminohippurate (PAH) is distinctly diminished. The same is true for dopamine. This depressive effect could be proved by measurement(More)
Sol-gel derived glasses based on SiO 2-CaO were studied with and without Zn as doping element. Investigations of their in vitro bioactivity were performed by soaking the glass powders in biological fluids for time periods up to 4 days. The surface reactions were characterized at the micrometer scale and with a high level of efficiency for both major and(More)
Peroxide containing PDMS were synthesized according to a new pathway. Although hydrosilylation is one of the main reaction carried out in silicone chemistry, the catalysts used are very sensitive to the chemical nature of the reactants and remained inefficient to graft allylic peroxide. Radical catalyzed thiol-ene chemistry was involved for the first time(More)