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Generation of novel, potent urotensin-II receptor antagonists by alkylation-cyclization of isoindolinone C3-carbanions
Abstract We report a facile alkylation–cyclization reaction involving the isoindolinone C3 position, which resulted in tricyclic derivatives 2 and 10 in 48% and 32% yields, respectively. These novelExpand
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The structure of the Golgi apparatus: a sperm’s eye view in principal epithelial cells of the rat epididymis
Abstract The Golgi apparatus of epididymal principal cells shares many structural features with other cell types. Saccular regions are arranged in a cis-Golgi network, eight flattened saccules, andExpand
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Contents Vol. 196, 2012
Quantitating the Percutaneous Absorption of Mechanistically Defined Chemical Mixtures
Abstract : The focus of this research was to assess the dermal absorption and skin toxicity of topically applied jet fuels Jet A, JP-8, JP-8(100) using pigs, in vitro porcine skin and inert membraneExpand