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No new chemotherapy agents have been developed recently that present hope for improving survival in patients with colon or rectal cancer. We undertook this study to investigate a new route of administering an old drug, 5-fluorouracil (5-FU). Sixty-six patients with advanced primary colon or rectal cancer were randomized to receive 12 cycles with increasing(More)
The explosive growth in the availability of information is overwhelming traditional information management systems. Although individual pieces of information have become easy to find, the larger context in which they exist has become harder to track. These contextual questions are ideally suited to visualization since the human visual system is remarkably(More)
A battery of instruments dealing with family social environment and family and child characteristics and behavior was administered to 115 families with children in TMR classes. Cluster analysis was performed on the social environment variables. Five distinctive clusters of families, each with distinctive patterns of characteristics, were identified:(More)
The explosive growth in the availability of information is overwhelming traditional information management systems. Although individual pieces of information have become easy to find, the larger context in which they exist has become harder to track. These contextual questions are ideally suited to visualization since the human visual system is remarkably(More)
The reciprocal relationship between home environment and social competency of 112 TMR adolescents was examined over a period of 3 years. Assessment of home environment included child-rearing attitudes, educationally relevant stimuli and opportunities available at home, and general psychosocial climate among family members. Measures of social competency(More)
To help fill the relative void of information about families of severely mentally retarded school children, we described 53 such families comparatively with 54 families of EMR and 50 of TMR children. All children resided in their natural homes; families were selected for study by identical means and interviewed at their home. Selection for comparison was(More)
The purpose of this study was to compare in vitro shear bond strength with three different enamel surface preparations: (1) 37% phosphoric acid etch, (2) sulfated polyacrylic acid etch with removal of crystals by vigorous rinsing and (3) polyacrylic acid etch with crystal growth. Forty extracted human premolar teeth were divided into four groups of ten.(More)