Charles E. Gragg

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Arabinose 5-phosphate ( A5P ) isomerase is a key enzyme in the biosynthesis of lipopolysaccharide, an essential component of the outer membrane of Gram-negative bacteria. The mechanism of the isomerase is envisioned to involve an enediol intermediate. A series of compounds, which are analogues of the substrates or intermediate, were tested as inhibitors of(More)
Within the soope of ASTM Committee E49 on Computerization of Material and Chemical Property Data, subcommittee E49.5 1 on Chemical Structural Information (CSI) has developed a draft of a standard specification for computerized CSI, focused on information content. This paper reports on recent progress to reach consensus made at ASTM meetings and urges(More)
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