Charles D. Gottlieb

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BACKGROUND Conventional activation mapping is difficult without inducible, stable ventricular tachycardia (VT). METHODS AND RESULTS We evaluated 16 patients with drug refractory, unimorphic, unmappable VT. Nine patients had ischemic and 7 had nonischemic cardiomyopathy. All patients had implantable defibrillators and had experienced 6 to 55 VT episodes(More)
OBJECTIVES This study sought to characterize the electrocardiographic patterns predictive of left ventricular sites of origin of repetitive monomorphic ventricular tachycardia (RMVT). BACKGROUND RMVT typically arises from the right ventricular outflow tract (RVOT) in patients without structural heart disease. The incidence of left ventricular sites of(More)
The purpose of this investigation was to develop an algorithm on the basis of the QRS morphology observed on the 12-lead ECG that would rapidly locate the site of origin of the monomorphic ventricular tachycardia arising from the septal portion of the RVOT. Radiofrequency catheter ablation guided by pace-mapping techniques has proven effective in(More)
BACKGROUND The CABG Patch trial compared prophylactic implantable cardiac-defibrillator (ICD) implantation with no antiarrhythmic therapy in coronary bypass surgery patients who had a left ventricular ejection fraction <0.36 and an abnormal signal-averaged ECG. There were 102 deaths among the 446 ICD group patients and 96 deaths among the 454 control group(More)
Pace mapping used to locate the site for ablation of idiopathic right ventricular outflow tract (RVOT) ventricular tachycardia remains difficult and time-consuming. A method to facilitate pace mapping and the most common site of ablation of this tachycardia are reported. In 18 consecutive patients with RVOT ventricular tachycardia, electrocardiographic(More)
A new low-frequency (9 MHz, 9 Fr) catheter-based ultrasound (US) transducer has been designed that allows greater depth of cardiac imaging. To demonstrate the imaging capability and clinical utility, intracardiac echocardiography (ICE) using this lower frequency catheter was performed in 56 patients undergoing invasive electrophysiological procedures.(More)
OBJECTIVES We sought to 1) correlate conduction block in the isthmus of the right atrium between the inferior vena cava and the tricuspid annulus with the efficacy of catheter ablation of type I atrial flutter, and 2) characterize the effects of ablative lesions on the properties of isthmus conduction. BACKGROUND There are few data on the mechanism of(More)
BACKGROUND In the present study, we examined the predictors of outcome of 103 patients with coronary artery disease and left ventricular dysfunction who had life-threatening ventricular arrhythmias and were treated with implantable cardioverter-defibrillators with the use of single-photon emission computed tomography (SPECT). METHODS AND RESULTS During a(More)
Uniform success for ablation of focal atrial tachycardias has been difficult to achieve using standard catheter mapping and ablation techniques. In addition, our understanding of the complex relationship between atrial anatomy, electrophysiology, and surface ECG P wave morphology remains primitive. The magnetic electroanatomical mapping and display system(More)
Magnetic resonance imaging (MRI) generates potent electromagnetic forces in the form of a static, gradient, or pulsed radiofrequency magnetic field that can result in pacemaker malfunction. This report documents a case of rapid cardiac pacing during MRI in a patient with a dual chamber pacemaker. Although the mechanism of rapid cardiac pacing is unclear, it(More)