Charles Blizzard

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INTRODUCTION The purpose of the present study was to examine the potential ocular and systemic toxicity and toxicokinetics/pharmacokinetics of sustained-release dexamethasone in canines. METHODS In this non-randomized study, intracanalicular depots (dexamethasone-loaded or placebo vehicle) were inserted into both eyes of 33 beagles. Tear fluid and plasma(More)
278 by animals such as squid, cuttlefish, knifefish, and seahorses. It is characterized by undulatory motion that creates traveling waves along the fin (Fig. 1). Researchers at the JHU Whiting School of Engineering and the Zanvyl Krieger School of Arts and Sciences conducted observational experiments, obtained maneuvering/propulsion characteristics of(More)
PURPOSE To examine the pharmacokinetic characteristics of sustained-release dexamethasone depots in two separate canine studies. METHODS Dexamethasone depots loaded with a clinically representative (0.4 mg) dose (DEXTENZA™; Ocular Therapeutix) or an elevated (0.7 mg) dose were inserted into the canaliculi of beagle eyes (n = 37 and n = 34, respectively).(More)
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