Learn More
Target of rapamycin (TOR) forms two conserved, structurally distinct kinase complexes termed TOR complex 1 (TORC1) and TORC2. Each complex phosphorylates a different set of substrates to regulate cell growth. In mammals, mTOR is stimulated by nutrients and growth factors and inhibited by stress to ensure that cells grow only during favorable conditions.(More)
During embryonic development, vascular networks remodel to meet the increasing demand of growing tissues for oxygen and nutrients. This is achieved by the pruning of redundant blood vessel segments, which then allows more efficient blood flow patterns. Because of the lack of an in vivo system suitable for high-resolution live imaging, the dynamics of the(More)
Prior practices such as waterfall software development, project management, and IT process frameworks are being questioned, and workforce requirements changing in response. IT education must keep current with these digital trends. Present programs and curricula do not adequately meet the rapidly emerging demand for digitally-skilled professionals. To(More)
  • 1