Charles B. Harris

Learn More
OBJECTIVE To answer the question 'does TNF blockade therapy enable people with severe AS to return to work or work more productively?'. METHODS All patients with AS currently receiving anti-TNF therapy at two UK Hospitals were asked to complete a questionnaire. This asked about occupational history, type of work, degree of job-related physical activity,(More)
Biotechnology Directorate. We thank P. Skelton and J. B. Lester for assistance with, respectively, mass spectrometry and DNA sequencing; A. L. Cutter for authentic samples of triketide lactones; H. A. I. McArthur and J. Dirlam for helpful discussions; and D. Hopwood and C. Khosla for the kind provision of S. coelicolor CH999 and plasmid pRM5. We also wish(More)
The dynamics of excited electrons in insulator quantum well states on a metal substrate were determined by femtosecond two-photon photoemission for the first time. Lifetimes are reported for the first three excited states for 1– 6 atomic layers of Xe on Ag(111). As the image states evolve into quantum well states with increasing coverage, the lifetimes(More)
Two-photon photoemission is a promising new technique that has been developed for the study of electron dynamics at interfaces. A femtosecond laser is used to both create an excited electronic distribution at the surface and eject the distribution for subsequent energy analysis. Time- and momentum-resolved two-photon photoemission spectra as a function of(More)
The mechanism of intermolecular ligand exchange has been studied using transition path sampling (TPS) based molecular dynamics (MD) simulations. Specifically, the exchange of solvent molecules bound to unsaturated Cr(CO)5 in methanol solution has been investigated. The results of the TPS simulations have shown that there are multiple steps in the reaction(More)
A foray into the exploration of Fe analogues of the (fulvalene)tetracarbonyldiruthenium [FvRu2(CO)4] solar-thermal storage system 1⇆2 is described. It was facilitated by the development of a convenient synthetic access to the parent [FvFe2(CO)4] 3a and the more soluble di(tert-butyl)fulvalene derivatives 3c and d. Laboratory time scale irradiations (>400(More)
We report the observation of a solvent-dependent spin state equilibrium in the 16-electron photoproduct CpCo(CO). Time-resolved infrared spectroscopy has been used to observe the concurrent formation of two distinct solvated monocarbonyl photoproducts, both of which arise from the same triplet CpCo(CO) precursor. Experiments in different solvent(More)
A phthalocyanine/Ag(111) interface state is observed for the first time using time- and angle-resolved two-photon photoemission. For monolayer films of metal-free (H2Pc) and iron phthalocyanine (FePc) on Ag(111), the state exists 0.23 ± 0.03 and 0.31 ± 0.03 eV above the Fermi level, respectively. Angle-resolved spectra show the state to be highly dispersive(More)