Learn More
RUPTURE of a papillary muscle is a rare complication of myocardial infarction.1 2 The combination of coronary artery disease with severe mitral regurgitation usually results in a rapid, deteriorating course. Not until 1948 was this diagnosis correctly made ante mortem.3 Sanders et al., in 1957, discussed 61 cases of rupture of a papillary muscle and pointed(More)
The purpose of this study was to evaluate the effect of hyperosmolality on the performance of, and the collateral blood flow to, ischemic myocardium. The myocardial response to mannitol, a hyperosmolar agent which remains extracellular, was evaluated in anesthetized dogs. Mannitol was infused into the aortic roots of 31 isovolumic hearts and of 15 dogs on(More)
The effect of intra-aortic counterpulsation (IACP) with a balloon upon myocardial oxygen consumption (MVo 2), coronaiy blood flow (TCF), and left ventricular performance was studied in 23 anesthetized canine right heart bypass preparations at constant heart rate and cardiac output. In nonhypotensive, nonTCF-limited preparations, IACP produced a fall in left(More)