Charles A. Morrissey

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It is well known that the mean root square displacement of random walks defined on integer lattice Z d follows the power law Cn 1/2 in all dimensions. Moreover such random walks are recurrent in d = 1, 2 and transient in d ≥ 3. In this project we investigate the behavior of random walks defined on other graphs. More specifically we determine the mean root(More)
Clusterin was first characterized as an apoptosis-associated transcript after it was identified as testosterone-repressed prostate message (TRPM-2) that is expressed in the epithelial cells of the regressing rat ventral prostate. Increases in clusterin mRNA and protein have been consistently detected in apoptotic cell death paradigms, establishing clusterin(More)
Clusterin is a 75-80 kDa heterodimenc glycoprotein that was first identified as a component of the fluid from the ram rete testes (Fritz et al, 1983). Over the past 15 years, the protein has been purified, or its cognate mRNA cloned, from a number of different species and diverse tissues, including several tissues of the reproductive tract (see Table 1).(More)
We have developed and validated a robust antigen capture assay for the measurement of serum clusterin. Increased clusterin expression, and alterations in serum clusterin levels have been associated with a number of disease states. In particular, clusterin has been shown to be associated with tissue regression and apoptosis in the rat ventral prostate in(More)
After hormonal ablation, 90% of the secretory epithelial cells of the prostate undergo apoptosis, and the remaining cells are reorganized as the tissue is remodeled. Using differential display RT-PCR of total RNA extracted from the rat ventral prostate before and 4 days after castration, we have cloned and sequenced a number of complementary DNAs whose(More)
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