Charlene J Williams

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PURPOSE OF REVIEW Among the myriad of players in the calcification of cartilage, ANK is a relatively new entrant. It is a multipass transmembrane protein that regulates the transport of inorganic pyrophosphate between the cell and the extracellular space. Mutations in ANK result in two distinct calcification disorders: craniometaphyseal dysplasia and(More)
Ank is a multipass transmembrane protein that regulates the cellular transport of inorganic pyrophosphate. In the progressive ankylosis (ank) mouse, a premature termination mutation at glutamic acid 440 results in a phenotype characterized by inappropriate deposition of basic calcium phosphate crystals in skeletal tissues. Mutations in the amino terminus of(More)
BACKGROUND The Blau syndrome (MIM 186580), an autosomal dominant granulomatous disease, was previously mapped to chromosome 16p12-q21. However, inconsistent physical maps of the region and consequently an unknown order of microsatellite markers, hampered us from further refining the genetic locus for the Blau syndrome. To address this problem, we(More)
The combination of biochar (BC) with compost has been suggested to be a promising strategy to promote plant growth and performance, but although " synergistic " effects have been stated to occur, full-factorial experiments are few, and explicit tests for synergism are lacking. We tested the hypothesis that a combination of BC and spent mushroom substrate(More)
500 college biology students were asked to predict the axisymmetry (horizontal-vertical position) of the water surface and a swimming goldfish in a masked, sealed container. Subjects were shown the fish submerged in the semifilled container before it was slipped into a terry cloth stocking. The researcher then asked subjects to predict the position of the(More)
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