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PURPOSE To establish a correlation between putative iron content using susceptibility weighted imaging (SWI) phase and T2* weighted magnitude values in the basal ganglia and the thalamus as a function of age in healthy human brains. MATERIALS AND METHODS One hundred healthy adults (range, 20-69 years; mean, 43 years) were evaluated for this study using a(More)
BACKGROUND AND PURPOSE The mesencephalon is involved in a number of human neurodegenerative disorders and has been typically imaged with T1-, T2- and T2*-weighted methods. Our aim was to collect high-contrast susceptibility-weighted imaging (SWI) data to differentiate among and within the basic mesencephalic structures: namely, the red nucleus, substantia(More)
BACKGROUND AND PURPOSE It is well known that patients with MS tend to have abnormal iron deposition in and around the MS plaques, in the basal ganglia and the THA. In this study, we used SWI to quantify iron content in patients with MS and healthy volunteers. MATERIALS AND METHODS Fifty-two patients with MS were recruited to assess abnormal iron content(More)
PURPOSE To investigate the correlation of non-heme iron content in deep gray matter nuclei as a function of age using quantitative susceptibility mapping (QSM) from both whole-structural and regional perspectives. MATERIALS AND METHODS We studied a group of 174 normal subjects ranging from 20 to 69 years old and measured the magnetic susceptibility of(More)
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