Estimation and group comparison of survival curves are two very common issues in survival analysis. In practice, the Kaplan-Meier estimates of survival functions may be biased due to unbalanced distribution of confounders. Here we develop an adjusted Kaplan-Meier estimator (AKME) to reduce confounding effects using inverse probability of treatment weighting… (More)
Hierarchical models are widely used in medical research to structure complicated models and produce statistical inferences. In a hierarchical model, observations are sampled conditional on some parameters and these parameters are sampled from a common prior distribution. Bayes and empirical Bayes (EB) methods have been effectively applied in analyzing these… (More)
2000 ii To my husband Chaofeng Liu and our daughter Rena Liu.
Hierarchical models have a variety of applications, including multi-center clinical trials, local estimation of disease rates, longitudinal studies, risk assessment, and meta-analysis. In a hierarchical model, observations are sampled conditional on individual unit-specific parameters and these parameters are sampled from a mixing distribution. In… (More)