• Publications
  • Influence
The Role of Deleterious Substitutions in Crop Genomes
Populations continually incur new mutations with fitness effects ranging from lethal to adaptive. While the distribution of fitness effects of new mutations is not directly observable, many mutationsExpand
  • 48
  • 2
Development and Genetic Characterization of an Advanced Backcross-Nested Association Mapping (AB-NAM) Population of Wild × Cultivated Barley
The ability to access alleles from unadapted germplasm collections is a long-standing problem for geneticists and breeders. Here we developed, characterized, and demonstrated the utility of a wildExpand
  • 45
  • 2
angsd‐wrapper: utilities for analysing next‐generation sequencing data
High‐throughput sequencing has changed many aspects of population genetics, molecular ecology and related fields, affecting both experimental design and data analysis. The software package angsdExpand
  • 11
The role of deleterious substitutions in crop genomes
Populations continually incur new mutations with fitness effects ranging from lethal to adaptive. While the distribution of fitness effects (DFE) of new mutations is not directly observable, manyExpand
  • 2
Environmental Association Identifies Candidates for Tolerance to Low Temperature and Drought
Barley (Hordeum vulgare ssp. vulgare) is cultivated from the equator to the Arctic Circle. The wild progenitor species, Hordeum vulgare ssp. spontaneum, occupies a relatively narrow latitudinal rangeExpand
  • 2
The fate of deleterious variants in a barley genomic prediction population
Targeted identification and purging of deleterious genetic variants has been proposed as a novel approach to animal and plant breeding. This strategy is motivated, in part, by the observation thatExpand
  • 2
Discovery of barley gene candidates for low temperature and drought tolerance via environmental association
Barley is cultivated from the equator to the Arctic Circle. The wild progenitor species, Hordeum vulgare ssp. spontaneum, occupies a relatively narrow latitudinal range (~30 - 40° N) primarily at lowExpand
  • 2
Variants from "The role of deleterious substitutions in crop genomes"
There are two gzipped VCF (variant call format) files with variant calls for barley and soybean. A total of 652,797 SNPs were identified in the barley lines, which consisted of 13 cultivars and 2Expand
The Fate of Deleterious Variants in a Barley Genomic Prediction Population
Targeted identification and purging of deleterious genetic variants has been proposed as a novel approach to animal and plant breeding. This strategy is motivated, in part, by the observation thatExpand