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BACKGROUND SOX2 is a member of SOX (SRY-related high mobility group box) family of transcription factors. METHODS In this study, we examined the expression of SOX2 in murine and human prostatic specimens by immunohistochemistry. RESULTS We found that SOX2 was expressed in murine prostates during budding morphogenesis and in neuroendocrine (NE) prostate(More)
Background: To determine the pattern of recurrence in patients with high-risk pathology at radical prostatectomy and to identify disease characteristics associated with clinical and biochemical recurrence (BCR). Methods: We identified 893 patients who underwent radical prostatectomy between January 2000 and June 2009 with pathologic T3N0 disease or T2N0(More)
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