Chaochao Xiong

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In May 2014, China formally confirmed the first human infection with the novel H5N6 avian influenza virus (AIV) in Sichuan Province. Before the first human case was reported, surveillance of AIVs in wild birds resulted in the detection of three H5N6 viruses in faecal samples from migratory waterfowl in Chenhu wetlands, Hubei Province, China. Genetic and(More)
Plasmid DNA vaccines are considered alternatives to inactivated influenza virus vaccines to control influenza. Vaccination with a hemagglutinin (HA)-, HA ectodomain (HAe)-, or HA subunit 1 (HA1)-based vaccine can stimulate protective immunity in animals. The aim of this study was to compare their capacity to induce an antibody response and protection(More)
A highly sensitive electrochemical immunosensor for avian influenza A (H7N9) virus (H7N9 AIV) detection was proposed by using electrochemical magnetoimmunoassay coupled with biometallization and anodic stripping voltammetry. This strategy could accumulate the enzyme-generated product on the surface of the magneto electrode by means of silver deposition,(More)
Novel avian influenza A(H7N9) virus was isolated in fatal patients in Yangtze River Delta of China in March 2013. We aimed to screen the virus in febrile patients in a tertiary hospital in an area with confirmed cases. Throat-swab specimens collected from consecutive patients with fever (≥38°C) and flu-like symptoms from April 15 to April 25, 2013 were(More)
Bifunctional magnetic nanobeads (bi-MBs) were fabricated by co-immobilizing target recognition molecules and signal molecules on a magnetic nanobead surface, which were used as both separation and enrichment carriers and signal carriers. The bi-MBs could capture and separate avian influenza A (H7N9) virus (H7N9 AIV) from complex samples efficiently based on(More)
An avian influenza virus strain, A/domestic green-winged teal/Hunan/2036/2007(H3N6) (DGW-T2036), was isolated from healthy domestic green-winged teals (Anas crecca) in Hunan Province, South China. All eight gene segments of the isolate were sequenced. Genomic analysis demonstrated that this H3N6 virus is a novel reassortant avian influenza virus with a gene(More)
An avian influenza virus strain, A/domestic green-winged teal/Hunan/3450/2006(H5N1) (DGW-T3450), was isolated from domestic green-winged teals. Genome analysis demonstrated that DGW-T3450 is a novel reassortant strain. The hemagglutinin (HA) and neuraminidase (NA) genes of this strain originated from H5N1 viruses circulating in poultry, while its remaining(More)
How to efficiently design and synthesize multifunctional molecules is particularly challenging. In this presentation, we devote to constructing a kind of simple structures with composite functionalities through straightforward preparation. Starting from common commercially available materials, the titled cis/trans-tetraarylethenes can be conveniently(More)
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