Chao-Yang Wang

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Osteoblasts play a crucial role in bone formation. However, the molecular mechanisms involved in osteoblast differentiation remain largely unclear. Runt-related gene 2 (Runx2) is a master transcriptional factor for osteoblast differentiation. Here we reported that p300/CBP-associated factor (PCAF) directly binds to Runx2 and acetylates Runx2, leading to an(More)
BACKGROUND If the emphysema lesions are not symmetrical, unilateral lung volume reduction surgery (LVRS) can be carried out on the more severe side. The aim of this research was to evaluate the feasibility and effects of LVRS performed simultaneously with resection of pulmonary and esophageal neoplasms. METHODS Forty-five patients with pulmonary neoplasm(More)
Myelin-derived proteins, such as tenascin-R (TN-R), myelin associate glycoprotein (MAG), and Nogo-A, inhibit the CNS regeneration. By targeting specifically the inhibitory epitopes, we have investigated whether vaccination with a recombinant DNA molecule encoding multiple domains of myelin inhibitors may be useful in CNS repair. We show here that the(More)
Cerebrospinal fluid (CSF) dopamine levels were studied in 16 male patients who also were tested for self-reported extraversion using the Eysenck Personality Inventory. Log CSF dopamine was significantly correlated with extraversion as predicted by recent theoretical work integrating mesolimbic dopamine function and active responding to external incentives(More)
We report Nogo-A as an oligodendroglial component congregating and interacting with the Caspr-F3 complex at paranodes. However, its receptor Nogo-66 receptor (NgR) does not segregate to specific axonal domains. CHO cells cotransfected with Caspr and F3, but not with F3 alone, bound specifically to substrates coated with Nogo-66 peptide and GST-Nogo-66.(More)
High-power lithium ion batteries are often rated with multiple current and voltage limits depending on the duration of the pulse event. These variable control limits, however, are difficult to realize in practice. In this paper, a linear Kalman filter based on a reduced order electrochemical model is designed to estimate internal battery potentials,(More)
3.8.2. Temperature Distribution Measurements 4749 3.8.3. Two-Phase Visualization 4750 3.8.4. Experimental Validation 4751 3.9. Modeling the Catalyst Layer at Pore Level 4751 3.10. Summary and Outlook 4752 4. Direct Methanol Fuel Cells 4753 4.1. Technical Challenges 4754 4.1.1. Methanol Oxidation Kinetics 4754 4.1.2. Methanol Crossover 4755 4.1.3. Water(More)
Lithium ion (Li-ion) batteries provide high energy and power density energy storage for diverse applications ranging from cell phones to hybrid electric vehicles (HEVs). For efficient and reliable systems integration, low order dynamic battery models are needed. This paper introduces a general method to generate numerically a fully observable/controllable(More)
OBJECTIVE To investigate the clinical effects of electroacupuncture (EA) at Fenglong (ST 40) on blood lipids. METHODS Two hundred and four patients of hyperlipidemia were randomly divided into a Fenglong group and a Xuezhikang group, 102 cases in each group. The patients in the Fenglong group were treated with electroacupuncture at Fenglong (ST 40). After(More)
Insect baculoviruses are capable of infecting mammalian glial cells in the central nervous system. We investigated in the current study the feasibility of using the viruses as toxin gene vectors to eliminate malignant glioma cells in the brain. We first confirmed that glioma cells were permissive to baculovirus infection, with variable transduction(More)