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- Zhiwu Zhang, Elhan S. Ersoz, +8 authors Edward S. Buckler
- Nature Genetics
- 2010
Mixed linear model (MLM) methods have proven useful in controlling for population structure and relatedness within genome-wide association studies. However, MLM-based methods can be computationally… (More)
- Marju Orho-Melander, Olle Melander, +38 authors Sekar Kathiresan
- Diabetes
- 2008
OBJECTIVE
Using the genome-wide association approach, we recently identified the glucokinase regulatory protein gene (GCKR, rs780094) region as a novel quantitative trait locus for plasma… (More)
- Chaorong Tang, M. J. S. Yang, +39 authors Huasun Huang
- Nature Plants
- 2016
The Para rubber tree (Hevea brasiliensis) is an economically important tropical tree species that produces natural rubber, an essential industrial raw material. Here we present a high-quality genome… (More)
- Marta Garaulet, Yu-Chi Lee, +5 authors José Marìa Ordovàs
- The American journal of clinical nutrition
- 2009
BACKGROUND
Disruption of the circadian system may be causal for manifestations of the metabolic syndrome (MetS).
OBJECTIVE
The objective was to study the associations of 5 CLOCK polymorphisms with… (More)
- Chao-Qiang Lai, Katherine L. Tucker, +6 authors José M. Ordovás
- Human Genetics
- 2008
Older Puerto Ricans living in the continental U.S. suffer from higher rates of diabetes, obesity, cardiovascular disease and depression compared to non-Hispanic White populations. Complex diseases,… (More)
- Chao-Qiang Lai, E Shyong Tai, +5 authors José Marìa Ordovàs
- Journal of lipid research
- 2003
Singapore comprises three ethnic groups: Chinese (76.7%), Malays (14%), and Asian-Indians (7.9%). Overall, Singaporeans experience coronary heart disease rates similar to those found in the United… (More)
- Chao-Qiang Lai, Serkalem Demissie, +5 authors José Marìa Ordovàs
- Journal of lipid research
- 2004
Several polymorphisms in the APOA5 gene have been associated with increased plasma triglyceride (TG) concentrations. However, associations between APOA5 and lipoprotein subclasses, remnant-like… (More)
- Dolores Corella, Donna K Arnett, +9 authors José Marìa Ordovàs
- Clinical chemistry
- 2007
BACKGROUND
Apolipoprotein A-II (APOA2) plays an ambiguous role in lipid metabolism, obesity, and atherosclerosis.
METHODS
We studied the association between a functional APOA2 promoter polymorphism… (More)
- Aron M. Troen, Emily E. French, +4 authors Chao-Qiang Lai
- AGE
- 2006
Experimentally restricting dietary calories, while maintaining adequate dietary nutrient content, extends lifespan in phylogenetically diverse species; thus suggesting the existence of conserved… (More)
- Daruneewan Warodomwichit, Jian Shen, +11 authors José Marìa Ordovàs
- Obesity
- 2009
Serum adiponectin levels have been positively associated with insulin sensitivity and are decreased in type 2 diabetes (T2D) and obesity. Genetic and environmental factors influence serum adiponectin… (More)