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In this paper, we present the design of Aneka, a .NET based service-oriented platform for desktop grid computing that provides: (i) a configurable service container hosting pluggable services for discovering, scheduling and balancing various types of workloads and (ii) a flexible and extensible framework/API supporting various programming models including(More)
The oxygenated β-carotene derivative astaxanthin exhibits outstanding colouring, antioxidative and health-promoting properties and is mainly found in the marine environment. To satisfy the growing demand for this ketocarotenoid in the feed, food and cosmetics industries, there are strong efforts to develop economically viable bioprocesses alternative to the(More)
To identify susceptibility loci for schizophrenia, we performed a two-stage genome-wide association study (GWAS) of schizophrenia in the Han Chinese population (GWAS: 746 individuals with schizophrenia and 1,599 healthy controls; validation: 4,027 individuals with schizophrenia and 5,603 healthy controls). We identified two susceptibility loci for(More)
An ERF gene, LchERF , was cloned from L. chinense for the first time. Overexpression of LchERF conferred salt stress tolerance in transgenic tobacco lines during seed germination and vegetative growth. Ethylene-responsive transcription factors (ERFs) play important roles in tolerance to biotic and abiotic stresses by regulating the expression of(More)
The MapReduce programming model allows users to easily develop distributed applications in data centers. However, many applications cannot be exactly expressed with MapReduce due to their specific characteristics. For instance, Genetic Algorithms (GAs) naturally fit into an iterative style. That does not follow the two phase pattern of MapReduce. This paper(More)
This paper summarizes our experience designing and implementing BitVault: a content-addressable retention platform for large volumes of reference data -- seldom-changing information that needs to be retained for a long time. BitVault uses "smart bricks" as the building block to lower the hardware cost. The challenges are to keep management costs low in a(More)
We present parallel Schwarz type domain decomposition preconditioned recycling Krylov subspace methods for the numerical solution of stochastic elliptic problems, whose coefficients are assumed to be a random field with finite variance. Karhunen-Loève (KL) expansion and double orthogonal polynomials are used to reformulate the stochastic elliptic problem(More)
HiSMRfs, a file system with standard POSIX interface suitable for Shingled Magnetic Recording (SMR) drives, has been designed and developed. HiSMRfs can manage raw SMR drives and support random writes without remapping layer implemented inside SMR drives. To achieve high performance, HiSMRfs separates data and metadata storage, and manages them differently.(More)
Lumbrokinase (LK) is a group of serine proteases with strong fibrinolytic and thrombolytic activities and is useful for treating diseases caused by thrombus. Cholera toxin B subunit (CTB) has been widely used to facilitate antigen delivery by serving as an effective mucosal carrier molecule for the induction of oral tolerance. We investigate here the(More)