Learn More
—The requirement to reduce the computational cost of evaluating a point probability density estimate when employing a Parzen window estimator is a well-known problem. This paper presents the Reduced Set Density Estimator that provides a kernel-based density estimator which employs a small percentage of the available data sample and is optimal in the L 2(More)
We investigated the emergence of discriminative responses to pitch by recording 2-, 3-, and 4-month-old infants' electro-encephalogram responses to infrequent pitch changes in piano tones. In all age groups, infants' responses to deviant tones were significantly different from responses to standard tones. However, two types of mismatch responses were(More)
Hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels are encoded by HCN1-4 gene family and have four subtypes. These channels are activated upon hyperpolarization of membrane potential and conduct an inward, excitatory current Ih in the nervous system. Ih acts as pacemaker current to initiate rhythmic firing, dampen dendritic(More)
Aberrant matrix deposition is a hallmark of pulmonary fibrosis and is characterized by an imbalance between matrix deposition and degradation. We have previously shown that mice harboring a conditional deletion of the GTP-binding protein, Rac1, in macrophages are protected from asbestos-induced pulmonary fibrosis. To investigate the contribution of aberrant(More)
BACKGROUND Published data regarding the associations between genetic variants and asthma risk in Chinese population were inconclusive. The aim of this study was to investigate asthma susceptible genes in Chinese population. METHODS The authors conducted 18 meta-analyzes for 18 polymorphisms in 13 genes from eighty-two publications. RESULTS Seven(More)
The antibiotic susceptibility of Acinetobacter calcoaceticus-Acinetobacter baumannii complex strains recovered from the intensive care unit (ICU) of West China Hospital, Sichuan, PR China, from 2006 to 2009 was investigated. The identification of A. baumannii and analysis of carbapenemase-encoding genes and their relationship with ISAba1 were performed by(More)
A semantic link peer-to-peer (P2P) network specifies and manages semantic relationships between peers' data schemas and can be used as the semantic layer of a scalable Knowledge Grid. The proposed approach consists of an automatic semantic link discovery method, a tool for building and maintaining P2P semantic link networks (P2PSLNs), a semantic-based peer(More)
The -159C/T polymorphism in the CD14 gene has been implicated in susceptibility to asthma, but a large number of studies have reported inconclusive results. The aim of this study is to investigate the association between the -159C/T polymorphism in the CD14 gene and the risk of asthma by meta-analysis. We searched Pubmed, Embase, CNKI database, Wanfang(More)
In order to process speech and music, the auditory cortex must learn to process patterns of sounds. Our previous studies showed that with a stream consisting of a repeating (standard) sound, younger infants show an increase in the amplitude of a positive slow wave in response to occasional changes (deviants) in pitch or duration, whereas older infants show(More)
Bee venom (BV) has been used for millennia in Chinese traditional medicine to treat rheumatoid arthritis (RA). However, its components and mechanism remain unclear, which has hampered its development and application for the treatment of RA. In this study, we examined the anti-arthritis effects of melittin, which composes nearly 50% of the dry weight of(More)