Changyan Lin

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PURPOSE The CH-VAD is an implantable, fully magnetically suspended ventricular assist device developed by the China Heart Biomedical Corporation (Suzhou, China) for full cardiac support. This study was performed to evaluate the reliability, hemocompatibility and end-organ effects of CH-VAD in a 35-day animal model trial. METHODS The pump was implanted in(More)
Effective anticoagulation regimens are needed to reduce risks of thrombosis and bleeding in animal models of ventricular assist device to verify its hemocompatibility, biologic safety and reliability. This study is to develop a validated anticoagulation procedure for a sheep model to test the newly developed CH-VAD. CH-VAD models were established in six(More)
OBJECTIVES This study reports the development and evaluation of a Computerized Mandarin Speech Test System (CMSTS). METHODS Taking into account the rules for developing speech materials and the unique linguistic characteristics of Mandarin, we designed and digitally recorded a set of materials comprised of seven lists of monosyllabic words, nine lists of(More)
The aim of the study was to use the ovine model to evaluate the hemocompatibility and end-organ effects of a newly developed magnetic suspension centrifugal left ventricular assist device (LVAD) by CH Biomedical Inc., Jiangsu, China. The LVADs were implanted in 6 healthy sheep, where inflow was inserted into the left ventricular apex and outflow was(More)
OBJECTIVE To evaluate the effects of self-made miniature axial flow blood pump as left ventricle assistance for postischemic heart. METHODS Sixteen adult healthy sheep were divided into two groups of 8 sheep. After acute left heart failure was induced by selective ligation of the left anterior descending branch of coronary artery for 1.5 hours and(More)
Aims: the purpose of this study was to develop a new left ventricular assist device which causes less blood damage. Methods: During design of the device, the method of Computational Fluid Dynamics (CFD) was used to optimize the device shape, number of impeller vanes, the structure and position of the guide vanes, and the size of the impeller screw-pitch.(More)
Hemolysis caused by blood pumps is a very important characteristic. In vitro hemolysis test circuits were constructed to operate the model I centrifugal pump, the model II axial flow pump, the magnetic coupling pump and the model I & II spiral mixed pump. The output of all pumps was set at flow 5 L/min, an average pressure of 100 mmHg. Experiments were(More)
BACKGROUND Electro-anatomical maps (EAM) and CT surface registration are widely used for catheter navigation in atrial fibrillation ablations. However, few studies have investigated the registration algorithm. Moreover, some of them are semiautomatic, so that physicians must be proficient; some are inaccurate for catheter navigation. A both automatic and(More)
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