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Osteoprotegerin (OPG) gene polymorphisms (T245G, T950C and G1181C) have been associated with osteoporosis and early predictors of cardiovascular disease. The aim of this study was to evaluate whether these polymorphisms contribute to cardiovascular disease (CVD) in type 2 diabetic patients. We performed a case-control study with 178 CVD subjects with(More)
The aim of the present study was to transfect rat aortic smooth muscle cells with an early growth response factor-1 (Egr-1)-specific DNAzyme (ED5), to observe its effect on Egr-1 and proliferating cell nuclear antigen (PCNA) expression and to elucidate the mechanism of ED5-mediated inhibition of vascular smooth muscle cell (VSMC) proliferation. VSMCs in(More)
We experimentally demonstrate an ultralow-threshold cascaded Brillouin microlaser for tunable microwave generation in a high-Q silica microsphere resonator. The threshold of the Brillouin microlaser is as low as 8 μW, which is close to the theoretical prediction. Moreover, the fifth-order Stokes line with a frequency shift up to 55 GHz is achieved with a(More)
This work presents a remarkably simple method for the fabrication of ultraviolet (UV)-curable adhesive bottle-like microresonators (BLMRs). The main fabrication process involves two steps: (1) creating liquid bottle-like microcavities along the taper waist of an optical fiber taper under interfacial tension and (2) curing the liquids into solids by UV light(More)
Endothelial cell injury plays a crucial role in the development and pathogenesis of cardiovascular disease. Vitexin is a natural flavonoid characterized by anti-oxidative and anti-inflammatory properties. The purpose of this study was to investigate the effects of vitexin on ox-LDL-induced endothelial dysfunction and to explore the underlying molecular(More)
We propose and experimentally demonstrate a simple scheme for generating optical frequency combs (OFCs) in a fiber-ring/microresonator laser system. The ultrahigh Q whispering gallery mode microresonator is employed both as a mode reflection mirror to generate erbium lasing and as a Kerr-nonlinearity initiator that introduces optical parametric oscillation(More)
We experimentally demonstrated a compact single-wall carbon-nanotube (SWNT)-based deep-red passively Q-switched Pr<sup>3+</sup>-doped ZBLAN all-fiber laser operating at 716 nm. A free-standing SWNT/polyvinyl alcohol composite film embedded between a pair of fiber connectors was employed as a saturable absorber (SA). The deep-red Q-switched operation is(More)
We demonstrate the first observation of stimulated Brillouin scattering (SBS) in a high-Q whispering gallery mode tellurite microsphere. Tellurite glass with composition of 70TeO₂-20ZnO-5Na₂O-5La₂O₃ (molar ratio) was prepared in-house using a melt-quenching technique. Moreover, tellurite microspheres with Q in excess of 13 millions at 1550 nm were(More)
Stimulated Brillouin scattering (SBS) in a microcavity is usually realized by employing a wavelength tunable external cavity diode laser (TECDL) as the pump source. In this Letter, we report the observation of SBS in a high Q microcavity based on a TECDL-free scheme. The microcavity is employed as a mode-reflecting mirror for constructing a fiber-ring laser(More)
Calcitonin gene-related peptide (CGRP) is an important cardioprotective neuropeptide. Few studies have shown that calcium supplementation may increase CGRP levels transiently. However, the relationship between CGRP and calcium is poorly known. This study was to explore the correlation between serum calcium and CGRP in coronary artery disease (CAD), and(More)