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Identification of prognostic biomarkers for breast cancer based on miRNA and mRNA co‐expression network
- Y. Yao, R. Liu, +8 authors Changgang Sun
- Biology, Medicine
- Journal of cellular biochemistry
- 1 September 2019
Breast cancer (BC) remains a serious health threat for women due to its high incidence and the trend of rejuvenation. Accumulating evidence has highlighted that microRNAs (miRNAs) and messenger RNAs… Expand
Integrative transcriptome data mining for identification of core lncRNAs in breast cancer
Background Cumulative evidence suggests that long non-coding RNAs (lncRNAs) play an important role in tumorigenesis. This study aims to identify lncRNAs that can serve as new biomarkers for breast… Expand
Comprehensive analysis of prognostic biomarkers in lung adenocarcinoma based on aberrant lncRNA–miRNA–mRNA networks and Cox regression models
Abstract Lung adenocarcinoma (LUAD) is the leading cause of cancer-related death worldwide, and its underlying mechanism remains unclear. Accumulating evidence has highlighted that long non-coding… Expand
Cardiotoxicity of doxorubicin-based therapy: What is the protective cognition that phytochemicals provide us?
Doxorubicin (DOX) continues to attract the interest of preclinical and clinical investigations despite its longer-than-50-year record of longevity. The clinical application of DOX can be regarded as… Expand
A four-mRNA model to improve the prediction of breast cancer prognosis.
BACKGROUND Breast cancer (BRCA) is the most prevalent cancer that threatens female health. A growing body of evidence has demonstrated the non-negligible effects of messenger RNAs (mRNAs) on… Expand
Identification of lncRNAs associated with lung squamous cell carcinoma prognosis in the competitive endogenous RNA network
Background Long noncoding RNAs (lncRNAs) play a role in the formation, development, and prognosis of various cancers. Our study aimed to identify prognostic-related lncRNAs in lung squamous cell… Expand
Genetic and epigenetic modifications of HPDL and SOX17 associated with breast cancer prognosis: a study based on The Cancer Genome Atlas
Deciphering of Key Pharmacological Pathways of Poria Cocos Intervention in Breast Cancer Based on Integrated Pharmacological Method
- Xiaoran Ma, Jibiao Wu, +9 authors Changgang Sun
- Biology, Medicine
- Evidence-based complementary and alternative…
- 9 October 2020
Objective Poria cocos (Fuling), a natural plant, has recently emerged as a promising strategy for cancer treatment. However, the molecular mechanisms of Poria cocos action in breast cancer remain… Expand
Multi-omics integrative analysis and survival risk model construction of non-small cell lung cancer based on The Cancer Genome Atlas datasets
Lung cancer is a major cause of cancer-associated mortality worldwide. However, the association between multi-omics data and survival in lung cancer is not fully understood. The present study… Expand
An mRNA characterization model predicting survival in patients with invasive breast cancer based on The Cancer Genome Atlas database.
- Huayao Li, Chundi Gao, +7 authors Changgang Sun
- Cancer biomarkers : section A of Disease markers
- 12 January 2021
BACKGROUND Invasive breast cancer is a highly heterogeneous tumor, although there have been many prediction methods for invasive breast cancer risk prediction, the prediction effect is not… Expand