Learn More
OBJECTIVE To investigate the molecular genetic background of VKH syndrome in Han Chinese by HLA-DRB genotyping. METHODS HLA-DRB genotyping was performed by PCR-SSOP method, then DR4 alleles were analyzed by SSOP and RFLP methods. RESULTS The frequency of DRB1 * 0405 was significantly higher in VKH patients than that in normal controls (80.4% vs 8.1%, Pc(More)
OBJECTIVE To access the association of HLA-DQA1 and -DQB1 alleles with Vogt-Koyanagi-Harada syndrome (VKH). METHODS The alleles in DQA1 and DQB1 loci of patients with VKH matched with 50 healthy controls were subtyped by polymerase chain reaction-sequence specific primer (PCR-SSP) and PCR-restriction fragment length polymorphism (PCR-RFLP). RESULTS DQA1(More)
AIM To record multifocal electroretinogram from different dosage of N(2)O(4) injected mice. In order to provide a foundation for further study. METHODS Normal winstar mice which were injected by different dosage of N(2)O(4) were studied for recording multifocal electroretinogram in the same time in the evening after N(2)O(4) injection. RESULTS The(More)
AIM To evaluate the effect of long-term weightlessness on retina and optic nerve in tail-suspension (TS) rats. METHODS A stimulated weightlessness model was established by suspending rats' tail. After 12wk, the ultrastructure and the number of optic nerve axons were observed by transmission electron microscope. The number of survival retinal ganglion(More)
OBJECTIVE To study the histopathologic changes of filtering blebs by subconjunctival application of perfluoropropane (C(3)F(8)) after trabeculectomy in rabbit eyes. METHODS Twenty rabbits were randomly divided into two groups, each group consisting of 10 rabbits. Trabeculectomy with topical application of C(3)F(8) was performed on one eye and(More)
  • 1