Chang Won Song

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Anginex synergizes with radiation therapy to inhibit tumor growth by radiosensitizing endothelial cells.

Ruud P M Dings, Brent Warren Williams, Chang Won Song, Arjan W Griffioen, Kevin H. Mayo, Robert J. Griffin
International journal of cancer
2005

We have demonstrated that the designed peptide anginex displays potent antiangiogenic activity. The aim of our study was to investigate the effect of anginex on established tumor vasculature as an… (More)

Radiation-induced vascular damage in tumors: implications of vascular damage in ablative hypofractionated radiotherapy (SBRT and SRS).

Heon Joo Park, Robert J. Griffin, Susanta Hui, Seymour H. Levitt, Chang Won Song
Radiation research
2012

We have reviewed the studies on radiation-induced vascular changes in human and experimental tumors reported in the last several decades. Although the reported results are inconsistent, they can be… (More)

Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells

Chang Won Song, Hyemi Lee, +5 authors Heon Joo Park
Scientific reports
2012

UNLABELLED The anti-cancer effects of metformin, the most widely used drug for type 2 diabetes, alone or in combination with ionizing radiation were studied with MCF-7 human breast cancer cells and… (More)

Simultaneous inhibition of the receptor kinase activity of vascular endothelial, fibroblast, and platelet-derived growth factors suppresses tumor growth and enhances tumor radiation response.

Robert J. Griffin, Brent Warren Williams, Robert Wild, Julie M. Cherrington, Heonjoo Park, Chang Won Song
Cancer research
2002

We have investigated the effect of simultaneous inhibition of multiple angiogenic growth factor signaling pathways on tumor growth, tumor blood perfusion, and radiation-induced tumor-growth delay… (More)

In vivo radioprotective effects of recombinant human granulocyte colony-stimulating factor in lethally irradiated mice.

Fatih M. Uckun, Iara Leão Luna de Souza, Kevin G. Waddick, Myra J. Wick, Chang Won Song
Blood
1990

The purpose of this study was to investigate the in vivo radioprotective effects of recombinant human granulocyte colony stimulating factor (rhG-CSF) in lethally irradiated BALB/c mice. We initially… (More)

Enhancement of tumor thermal therapy using gold nanoparticle-assisted tumor necrosis factor-alpha delivery.

Rachana K. Visaria, Robert J. Griffin, +4 authors John C. Bischof
Molecular cancer therapeutics
2006

Tumor necrosis factor-alpha (TNF-alpha) is a potent cytokine with anticancer efficacy that can significantly enhance hyperthermic injury. However, TNF-alpha is systemically toxic, thereby creating a… (More)

Radiobiological basis of SBRT and SRS

Chang Won Song, Mi-sook Kim, Lawrence Chinsoo Cho, Kathryn Ellen Dusenbery, Paul Wayne Sperduto
International Journal of Clinical Oncology
2014

Stereotactic body radiation therapy (SBRT) and stereotactic radiosurgery (SRS) have been demonstrated to be highly effective for a variety of tumors. However, the radiobiological principles of SBRT… (More)

Tumor reoxygenation and postirradiation vascular changes.

Jacob J. Clement, Noriaki Tanaka, Chang Won Song
Radiology
1978

Postirradiation reoxygenation kinetics of the Walker 256 carcinoma were examined and related to radiation-induced changes in tumor vascular functions. Changes in the hypoxic cell component of… (More)

Early changes in the functional vasculature of Walker carcinoma 256 following irradiation.

H.-L. Wong, Chang Won Song, Seymour H. Levitt
Radiology
1973

Increase in pO2 and radiosensitivity of tumors by Fluosol-DA (20%) and carbogen.

Chang Won Song, Intae Lee, Takeo Hasegawa, Juong G. Rhee, Seymour H. Levitt
Cancer research
1987

The potential usefulness of i.v. injection of perfluorochemicals and breathing carbogen (95% O2 and 5% CO2) to improve the radiation-induced control of tumors was investigated. When C3H mice, bearing… (More)

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