Chang Shu

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Warm‑supplementing kidney yang (WSKY) is an herbal prescription that has been used in Traditional Chinese Medicine for the treatment of psychiatric conditions. A previous study by our group found that WSKY significantly improved cognitive function of schizophrenia patients. In the present study, the effects of WSKY on cognitive function and their underlying(More)
OBJECTIVES To examine the effect of BDNF on F-actin during the stimulation of IL-1β in hippocampal neurons. MATERIALS & METHODS We cultured hippocampal neurons from rat embryos. Cell stimulation was induced by IL-1β. Cell culture success was evaluated by an activity analysis of CCK-8, staining of gliocyte by immunohistochemistry. Changes in F-actin, BDNF(More)
Several evidences have suggested that the brain-derived neurotrophic factor (BDNF) gene may be involved in the pathogenesis of bipolar disorder (BPD), but not all studies get the same result. The paper investigated two genetic polymorphisms of BDNF, C-270T and Val66Met, in a case-control design for their association with BPD. Sixty-seven patients of early(More)
Issue tracking is a core part of the software development process. For open source projects, the number of duplicate reports represents a significant percentage of the repository, numbering in the thousands of reports for popular projects. In this paper, we introduce an approach to suggest potential duplicate issue reports to the issue reporter who is(More)
Nowadays, software is regarded not only as a product but also as a kind of service provided to the end users. Software as a Service (SaaS) model is gradually adopted by more and more enterprises. It reduces the cost of hardware, maintenance, updating and many other services for end users. It enables users focus on their business areas. The model also(More)
We sought to determine the prevalence and correlates of valvular heart diseases (VHD) in the elderly population. The participants' personal information, medical history, behavioral habits and clinical status were assessed by questionnaire, while the left ventricular dimensions, function and the presence and severity of VHD were evaluated by transthoracic(More)
Inducing cellular dedifferentiation has been proposed as a potential method for enhancing endogenous regeneration in mammals. Here we demonstrate that phenotypic and functional neurons derived from adult rat bone marrow stromal stem cells (MSCs) can be induced to undergo dedifferentiation, then proliferation and redifferentiation. In addition to(More)