Chang-Sheng Mei

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MR thermometry can be a very challenging application, as good resolution may be needed along spatial, temporal, and temperature axes. Given that the heated foci produced during thermal therapies are typically much smaller than the anatomy being imaged, much of the imaged field-of-view is not actually being heated and may not require temperature monitoring.(More)
PURPOSE To present a dual-pathway multi-echo steady state sequence and reconstruction algorithm to capture T2, T2(∗) and field map information. METHODS Typically, pulse sequences based on spin echoes are needed for T2 mapping while gradient echoes are needed for field mapping, making it difficult to jointly acquire both types of information. A(More)
PURPOSE To combine MRI, ultrasound, and computer science methodologies toward generating MRI contrast at the high frame rates of ultrasound, inside and even outside the MRI bore. METHODS A small transducer, held onto the abdomen with an adhesive bandage, collected ultrasound signals during MRI. Based on these ultrasound signals and their correlations with(More)
PURPOSE Dual-pathway sequences have been proposed to help improve the temperature-to-noise ratio (TNR) in MR thermometry. The present work establishes how much of an improvement these so-called "PSIF-FISP" sequences may bring in various organs and tissues. METHODS Simulations and TNR calculations were validated against analytical equations, phantom,(More)
PURPOSE To describe how B0 inhomogeneities can cause errors in proton resonance frequency (PRF) shift thermometry, and to correct for these errors. METHODS With PRF thermometry, measured phase shifts are converted into temperature measurements through the use of a scaling factor proportional to the echo time, TE. However, B0 inhomogeneities can deform,(More)
MR-based thermometry is a valuable adjunct to thermal ablation therapies as it helps to determine when lethal doses are reached at the target and whether surrounding tissues are safe from damage. When the targeted lesion is mobile, MR data can further be used for motion-tracking purposes. The present work introduces pulse sequence modifications that enable(More)
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