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Radiation exposure to the patient has become a concern for the radiologist in the multidetector computed tomography (CT) era. With the introduction of faster multidetector CT scanners, various techniques have been developed to reduce the radiation dose to the patient; one method is automatic exposure control (AEC). AEC systems make use of different types of(More)
OBJECTIVE The purpose of this study was to investigate the ultrasonographic and pathologic findings of nonpalpable thyroid carcinomas and reliable guidelines for fine-needle aspiration (FNA). METHODS Our study was approved by our Institutional Review Board, and written informed consent was waived. Between April 2004 and June 2006, screening(More)
OBJECTIVE Finding the anthropometric measure of visceral obesity is essential to clinical practice, because it predicts cardiovascular and metabolic risks. Sagittal abdominal diameter (SAD) has been proposed as an estimate of visceral adipose tissue (VAT). The aim of the present study was to evaluate the usefulness of SAD in predicting visceral obesity by(More)
PURPOSE In an attempt to improve the oral bioavailability of paclitaxel, a novel P-glycoprotein inhibitor, KR30031, which is verapamil analog with fewer cardiovascular effects, was coadministered with paclitaxel, and to elucidate other possible causes of the low oral bioavailability of paclitaxel, an inhibitor of hepatic metabolism, ketoconazole, was also(More)
A variety of tumors, including primary malignant tumors, secondary malignant tumors, and benign tumors, can occur in the tracheobronchial tree. Primary malignant tumors commonly originate from the surface epithelium or the salivary glands, whereas most benign tumors arise from the mesenchymal tissue. At computed tomography (CT), primary malignant tumors(More)
The popularization of computed tomography (CT) in clinical practice and the introduction of mass screening for early lung cancer with the use of CT have increased the frequency of findings of subtle nodules or nodular ground-glass opacity. Nodular ground-glass opacity may be observed in malignancies such as bronchioloalveolar carcinoma and adenocarcinoma,(More)
PURPOSE To evaluate the potential of xenon ventilation computed tomography (CT) in the quantitative and visual analysis of chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS This study was approved by the institutional review board. After informed consent was obtained, 32 patients with COPD underwent CT performed before the administration(More)
OBJECTIVES To evaluate the efficacy of the computer-aided detection (CAD) system and thin-slab maximum intensity projection (MIP) technique in the detection of pulmonary nodules at multidetector computed tomography (CT) in patients who underwent metastatectomy. MATERIALS AND METHODS This retrospective study was approved by the institutional review board(More)
Induced pluripotent stem (iPS) cells have been generated from various somatic cells; however, a major restriction of the technology is the use of potentially harmful genome-integrating viral DNAs. Here, without a viral vector, we generated iPS cells from fibroblasts using a non-viral magnetic nanoparticle-based transfection method that employs biodegradable(More)
OBJECTIVE To evaluate the inter-group differences in growth and the pathological results of nodular ground-glass opacities (GGOs) according to their size and focal solid portions. MATERIALS AND METHODS Ninety-six nodular GGOs in 55 individuals followed by CT for at least one month from an initial chest CT were included. Forty nodular GGOs in 30(More)