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Imaging with 99mTc ECDG targeted at the multifunctional glucose transport system: feasibility study with rodents.
PURPOSE To evaluate the feasibility of technetium 99m ((99m)Tc) ethylenedicysteine-deoxyglucose (ECDG) imaging in tumor-bearing rodents. MATERIALS AND METHODS ECDG was synthesized by means ofExpand
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Prognostication of Recovery in Patients With Acute Ischemic Stroke Through the Use of Brain SPECT With Technetium-99m—Labeled Metronidazole
Background and Purpose— We hypothesized that technetium-99m-ethylene dicysteine-metronidazole (99mTc-EC-MN) localizes to brain tissue that is hypoxic but viable. This study prospectively evaluatedExpand
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Monitoring the effect of PEGylation on polyethylenimine in vivo using nuclear imaging technique.
Polyethyleneimine (PEI) has been extensively investigated for use as a nonviral gene delivery vector due to its "proton sponge" mechanism. This work monitored the effect of PEGylation in vivo usingExpand
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Patterns of Three-Phase Bone Scintigraphy According to the Time Course of Complex Regional Pain Syndrome Type I After a Stroke or Traumatic Brain Injury
We have proposed to evaluate different patterns represented on 3-phase bone scintigraphy (TPBS) according to the time course of complex regional pain syndrome (CRPS) type I (CRPS-I) after a stroke orExpand
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Pretreatment with Ursodeoxycholic Acid (UDCA) as a Novel Pharmacological Intervention in Hepatobiliary Scintigraphy
The purpose of this volunteer study was to investigate whether pretreatment with UDCA before the administration of 99mTc DISIDA affects the biliary excretion of the DISIDA, and whether it can shortenExpand
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Assessment of therapeutic tumor response using 99mtc-ethylenedicysteine-glucosamine.
PURPOSE The aim of this study was to evaluate 99mTc-ethylenedicysteine-glucosamine (EC-DG) for the assessment of tumor growth. METHOD To evaluate whether 99mTc-EC-DG is involved in cell nucleiExpand
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Hepatocyte-targeted nuclear imaging using 99mTc-galactosylated chitosan: conjugation, targeting, and biodistribution.
UNLABELLED Galactosyl-methylated chitosan (GMC) is a galactosylated chitosan (GC) that is chemically modified to improve labeling efficiency with (99m)Tc compared with native GC. The aim of thisExpand
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Imaging with 99 mTc ECDG Targeted at the Multifunctional Glucose Transport System : Feasibility Study with Rodents 1
1 From the Divisions of Diagnostic Imaging (D.J.Y., C.G.K., A.A., D.F.Y., C.S.O., J.L.B., J.J.W., E.E.K., D.A.P.) and Radiation Oncology (N.R.S.), University of Texas M.D. Anderson Cancer Center,Expand
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The Efficacy of Dual Time Point F-18 FDG PET Imaging for Grading of Brain Tumors
Purpose: Several studies have explored the usefulness of dual time point F-18 FDG positron emission tomography imaging (DTPI) in improving detection of brain metastases and tumors outside the brain,Expand
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Intratumoral Injection of 188Re labeled Cationic Polyethylenimine Conjugates: A Preliminary Report
188Re(Rhenium) is easily obtained from an in-house 188W/188Re generator that is similar to the current 99Mo/99mTc generator, making it very convenient for clinical use. This characteristic makes thisExpand
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