Chandrasekhar Ghosh

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Twenty-four selected non-O1/non-O139 Vibrio cholerae strains were examined for the presence of virulence associated genes like ctxA, tcpA, toxR and the repetitive sequence (RS element). Seventeen of these were isolated from diarrhoeal stool samples while the remaining seven were of local environmental origin. Nine and four respectively of these strains were(More)
Tea and coffee are widely consumed beverages across the world and they are rich sources of various polyphenols. Polyphenols are responsible for the bitterness and astringency of beverages and are also well known to impart antioxidant properties which is beneficial against several oxidative stress related diseases like cancer, cardiovascular diseases, and(More)
The photophysical properties of commercially available dye Acridine Orange (AO) describe an excellent probe for selective and sensitive detection of caffeine in aqueous solution. AO exists in monomer-dimer equilibrium in water. AO monomer is a fluorophore, but the dimer is not. Addition of caffeine to the AO leads to a shift in the monomer-dimer equilibrium(More)
A Vibrio cholerae O1 strain (1150) of the EIT or biotype and Ogawa serotype with haemagglutination (HA) activity was subjected to TnphoA mutagenesis. Out of several mutants isolated, one HA- and another HA+ mutant were further characterised. The HA- mutant showed about 50% reduction in its intestinal adherence capacity in vitro and about 9-fold decrease of(More)
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