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BacMet: antibacterial biocide and metal resistance genes database
Antibiotic resistance has become a major human health concern due to widespread use, misuse and overuse of antibiotics. In addition to antibiotics, antibacterial biocides and metals can contribute toExpand
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METAXA2: improved identification and taxonomic classification of small and large subunit rRNA in metagenomic data.
The ribosomal rRNA genes are widely used as genetic markers for taxonomic identification of microbes. Particularly the small subunit (SSU; 16S/18S) rRNA gene is frequently used for species- orExpand
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Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential
BackgroundAntibacterial biocides and metals can co-select for antibiotic resistance when bacteria harbour resistance or tolerance genes towards both types of compounds. Despite numerous case studies,Expand
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The structure and diversity of human, animal and environmental resistomes
BackgroundAntibiotic resistance genes (ARGs) are widespread but cause problems only when present in pathogens. Environments where selection and transmission of antibiotic resistance frequently takeExpand
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Metal Resistance and Its Association With Antibiotic Resistance.
Antibiotic resistance is recognised as a major global threat to public health by the World Health Organization. Currently, several hundred thousand deaths yearly can be attributed to infections withExpand
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Elucidating selection processes for antibiotic resistance in sewage treatment plants using metagenomics.
Sewage treatment plants (STPs) have repeatedly been suggested as "hotspots" for the emergence and dissemination of antibiotic-resistant bacteria. A critical question still unanswered is if selectionExpand
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Application of high-throughput pyrosequencing in the analysis of microbiota of food commodities procured from small and large retail outlets in a U.S. metropolitan area - A pilot study.
With the advent of high-throughput sequencing technologies, it is possible to comprehensively analyze the microbial community of foods without culturing them in the laboratory. The estimation of allExpand
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Does antifouling paint select for antibiotic resistance?
There is concern that heavy metals and biocides contribute to the development of antibiotic resistance via co-selection. Most antifouling paints contain high amounts of such substances, which risksExpand
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Untreated urban waste contaminates Indian river sediments with resistance genes to last resort antibiotics.
Efficient sewage treatment is critical for limiting environmental transmission of antibiotic-resistant bacteria. In many low and middle income countries, however, large proportions of sewage areExpand
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Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes
BackgroundHospital wastewaters contain fecal material from a large number of individuals, of which many are undergoing antibiotic therapy. It is, thus, plausible that hospital wastewaters couldExpand
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