Chan-juan Zhong

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Mast cells (MCs) deficient rats (Ws/Ws) were used to investigate the roles of MCs in visceral hyperalgesia. Ws/Ws and wild control (+/+) rats were exposed to T. spiralis or submitted to acute cold restraint stress (ACRS). Levels of proteinase-activated receptor 2 (PAR2) and nerve growth factor (NGF) were determined by immunoblots and RT-PCR analysis, and(More)
OBJECTIVE To explore whether bone marrow transplantation (BMT) can restore gastrointestinal mast cells in mast cell deficient (Ws/Ws) rats and understand the features of these reconstituted mast cells. METHODS Thirty-six Ws/Ws rats were subjected to Co(60) radiation at 6 gradient doses (6.0, 7.0, 8.0, 9.0, 10.0 and 11.0 Gy, n = 6) to confirm the(More)
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