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BACKGROUND AND OBJECTIVES The treadmill exercise test (TMT) is used as a first-line test for diagnosing coronary artery disease (CAD). However, the findings of a TMT can be inconclusive, such as incomplete or equivocal results. Aortic valve sclerosis (AVS) is known to be a good predictor of CAD. We determined the usefulness of assessing AVS on 2-dimensional(More)
Imatinib mesylate is a specific tyrosine kinase inhibitor that may block the platelet-derived growth factor and transforming growth factor pathways. These pathways are known to provoke fibroblast activation. We evaluated whether imatinib, by inhibiting these pathways, prevents diastolic dysfunction and attenuates myocardial remodeling using spontaneously(More)
BACKGROUND Vasospastic angina (VA) can occasionally cause acute myocardial infarction (AMI). METHODS AND RESULTS From January 2003 to June 2005, coronary spastic angina was diagnosed in 292 patients by performing spasm provocation tests. Among the 292 patients, 21 (7.2% of all the VA patients) had an AMI. There were 20 patients who initially visited the(More)
BACKGROUND Myocardial fibrosis is a feature of diastolic dysfunction and target organ damage, which was compared among subjects with normotension (NT), white-coat hypertension (WCH) and essential hypertension (EH). Serum procollagen type I propeptide (PIP) level was assessed as a marker of diastolic dysfunction in WCH. METHODS AND RESULTS Of 90 subjects,(More)
This report describes a case of acute mesenteric ischemia due to acute superior mesenteric artery (SMA) thromboembolism in a patient with chronic atrial fibrillation despite optimal anticoagulation therapy. The patient underwent SMA angiography and endovascular revascularization for acute mesenteric ischemia. We initially tried endovascular thrombolytic(More)
BACKGROUND Little is known about the relationship between resting electrocardiogram (ECG) parameters and the incidence of coronary heart disease (CHD). We sought to establish the association between ECG parameters and estimated 10-year risk for CHD. METHODS We applied the risk prediction algorithm used by the National Cholesterol Education Program Adult(More)
BACKGROUND AND OBJECTIVES The early morning blood pressure surge (EMBPS) has been reported to be associated with cardiovascular events. The aim of this study was to investigate the relationship between 24-hour ambulatory BP monitoring (ABPM) parameters and conventional cardiovascular risk factors. SUBJECTS AND METHODS Patients (n=346) never-treated for(More)
BACKGROUND We compared the results of laboratory examinations, echocardiography, arterial stiffness, central blood pressure (BP) and ambulatory BP monitoring (ABPM) between treatment-naïve patients with low normal thyroid-stimulating hormone (TSH) and those with high normal TSH levels. METHODS A total of 285 consecutively-eligible patients with both(More)
Non-carious cervical lesion (NCCL) is the loss of hard dental tissue commonly observed at the buccal and labial tooth surfaces at the cementoenamel junction (CEJ). Most NCCLs of teeth can be classified into four categories: attrition, erosion, abrasion, and stress-induced cervical lesion. Stress-induced cervical lesions are loss of tooth structure that(More)