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- Paolo Fiorina, Mollie M. Jurewicz, +14 authors Reza Abdi
- Journal of immunology
- 2009
Human clinical trials in type 1 diabetes (T1D) patients using mesenchymal stem cells (MSC) are presently underway without prior validation in a mouse model for the disease. In response to this void,… (More)
- Andrea Heinzmann, Xin Qing Mao, +29 authors Klaus A. Deichmann
- Human molecular genetics
- 2000
Asthma and atopy show epidemiological association and are biologically linked by T-helper type 2 (T(h)2) cytokine-driven inflammatory mechanisms. IL-4 operates through the IL-4 receptor (IL-4R, a… (More)
- Alexander J Stokes, Lori M.N. Shimoda, Murielle Koblan-Huberson, Chaker N. Adra, Helen Turner
- The Journal of experimental medicine
- 2004
Cutaneous mast cell responses to physical (thermal, mechanical, or osmotic) stimuli underlie the pathology of physical urticarias. In vitro experiments suggest that mast cells respond directly to… (More)
Mesenchymal stem cells (MSCs) are pluripotent stromal cells that have the potential to give rise to cells of diverse lineages. Interestingly, MSCs can be found in virtually all postnatal tissues. The… (More)
- Chaker N. Adra, Shanshan Zhu, +7 authors Bentley Lim
- Genomics
- 1996
While a large body of knowledge about cell membrane proteins exists, much less is known about the repertoire and function of integral membrane proteins of intracellular organelles. In looking for… (More)
- Kazuhiko Arima, Ritsuko Umeshita-Suyama, +16 authors Kenji Izuhara
- The Journal of allergy and clinical immunology
- 2002
BACKGROUND
A substantial body of evidence exists to support the pivotal role of IL-13 in the pathogenesis of bronchial asthma. We recently found that a variant of the IL13 gene (Arg110Gln) is… (More)
- Monther Al-Alwan, Safiah Olabi, +5 authors Chaker N. Adra
- PloS one
- 2011
The actin-bundling protein, fascin, is a member of the cytoskeletal protein family that has restricted expression in specialized normal cells. However, many studies have reported the induction of… (More)
- José Luis Donato, Jon Ko, +7 authors Chaker N. Adra
- The Journal of clinical investigation
- 2002
Proper control of cell cycle progression is critical for the constant self-renewal, differentiation, and homeostasis of the hematopoietic system. Cells of all types share the common cell cycle… (More)
- Hazem Ghebeh, Ghida Majed Sleiman, +6 authors Chaker N. Adra
- BMC Cancer
- 2013
Accumulating evidence supports cancer to initiate and develop from a small population of stem-like cells termed as cancer stem cells (CSC). The exact phenotype of CSC and their counterparts in normal… (More)
- Jason C. Barnhill, Alexander J Stokes, +4 authors Helen Turner
- Journal of cellular biochemistry
- 2004
TRPV ion channels transduce a range of temperature stimuli. We proposed that analysis of the protein-protein interactions made by TRPV2 might give insight into the key issues surrounding this… (More)