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Molecular genetics of the swine major histocompatibility complex, the SLA complex.

• Joan K. Lunney, Chak-Sum Ho, Michal Wysocki, Douglas M. Smith
• Developmental and comparative immunology
• 2009

The swine major histocompatibility complex (MHC) or swine leukocyte antigen (SLA) complex is one of the most gene-dense regions in the swine genome. It consists of three major gene clusters, the SLA… (More)

Characterization of swine leukocyte antigen polymorphism by sequence-based and PCR-SSP methods in Meishan pigs

• Chak-Sum Ho, Erin S. Rochelle, Gregory W. Martens, Lawrence B. Schook, Douglas M. Smith
• Immunogenetics
• 2006

Resource herds of swine leukocyte antigen (SLA)-characterized pigs are an important tool for the study of immune responses, disease resistance, and production traits. They are also valuable large… (More)

Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy

• Kristine Yee, Konstantinos G Malliaras, +16 authors Eduardo Marbán
• PloS one
• 2014

BACKGROUND Epicardial injection of heart-derived cell products is safe and effective post-myocardial infarction (MI), but clinically-translatable transendocardial injection has never been evaluated.… (More)

Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction.

• Konstantinos G Malliaras, Rachel Ruckdeschel Smith, +16 authors Eduardo Marbán
• Circulation
• 2013

BACKGROUND Magnetic resonance imaging (MRI) in the CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction (CADUCEUS) trial revealed that cardiosphere-derived cells (CDCs)… (More)

Molecular characterization of swine leukocyte antigen gene diversity in purebred Pietrain pigs.

• Sabine E. Essler, Werner Ertl, +7 authors Armin Saalmueller
• Animal genetics
• 2013

The porcine major histocompatibility complex (MHC) harbors the highly polymorphic swine leukocyte antigen (SLA) class I and II gene clusters encoding glycoproteins that present antigenic peptides to… (More)

IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex

• Giuseppe Maccari, James Robinson, +9 authors Steven G. E. Marsh
• Nucleic Acids Research
• 2017

The IPD-MHC Database project (http://www.ebi.ac.uk/ipd/mhc/) collects and expertly curates sequences of the major histocompatibility complex from non-human species and provides the infrastructure and… (More)

Curative ex vivo liver-directed gene therapy in a pig model of hereditary tyrosinemia type 1.

• Raymond D. Hickey, Shennen A. Mao, +19 authors Scott L. Nyberg
• Science translational medicine
• 2016

We tested the hypothesis that ex vivo hepatocyte gene therapy can correct the metabolic disorder in fumarylacetoacetate hydrolase-deficient (Fah(-/-)) pigs, a large animal model of hereditary… (More)

Preferred SLA class I/class II haplotype combinations in German Landrace pigs

• Ulrike Gimsa, Chak-Sum Ho, Sabine Hammer
• Immunogenetics
• 2016

Major histocompatibility complex (MHC) molecules are responsible for the antigen presentation to T lymphocytes. High recombination rates in the MHC genes, as observed in humans, are believed to serve… (More)

T Cell Lymphoma and Leukemia in Severe Combined Immunodeficiency Pigs following Bone Marrow Transplantation: A Case Report

• Ellis J. Powell, Jared Graham, +14 authors Christopher K. Tuggle
• Front. Immunol.
• 2017

After the discovery of naturally occurring severe combined immunodeficiency (SCID) within a selection line of pigs at Iowa State University, we found two causative mutations in the Artemis gene:… (More)

A critical analysis of quantitating flow cytometry: the role of the crossmatch in 2014.

• Jason Rosenberg, Arthur B. Eisenbrey, +5 authors Chak-Sum Ho
• Clinical transplants
• 2013

The mean fluorescent intensity obtained using single antigen beads does not represent the titer of the serum sample very well because the degree of saturation of the antigen on the bead varies by… (More)

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