Chae-Ryon Kong

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Previous studies of reentrant arrhythmias in the heart have been performed in computer models and tissue experiments. We hypothesized that confluent monolayers of cardiac cells can provide a simple, controlled, and reproducible experimental model of reentry. Neonatal rat ventricular cells were cultured on 22-mm-diameter coverslips and stained with the(More)
Although the prevailing view of mechanoelectric feedback (MEF) in the heart is in terms of longitudinal cell stretch, other mechanical forces are considerable during the cardiac cycle, including intramyocardial pressure and shear stress. Their contribution to MEF is largely unknown. In this study, mechanical stimuli in the form of localized fluid jet pulses(More)
Kong, Chae-Ryon, Nenad Bursac, and Leslie Tung. Mechanoelectrical excitation by fluid jets in monolayers of cultured cardiac myocytes. J Appl Physiol 98: 2328–2336, 2005. First published February 24, 2005; doi:10.1152/japplphysiol.01084.2004.—Although the prevailing view of mechanoelectric feedback (MEF) in the heart is in terms of longitudinal cell(More)
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