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  • Chad A. Middleton, Upendra Nongthomba, Katherine Parry, Sean T Sweeney, John C. Sparrow, Christopher J. H. Elliott
  • Biology, Medicine
  • BMC Biology
  • 2006 (First Published: 12 June 2006)
  • BackgroundThe processes by which eggs develop in the insect ovary are well characterized. Despite a large number of Drosophila mutants that cannot lay eggs, the way that the egg is moved along theContinue Reading
  • Deepak Singh, Bruce S. Hudson, Chad A. Middleton, Robert R. Birge
  • Chemistry, Medicine
  • Biochemistry
  • 2001 (First Published: 1 April 2001)
  • In the absence of a high-resolution diffraction structure, the orientation and conformation of the protonated Schiffs base retinylidinium chromophore of rhodopsin within the opsin matrix has been theContinue Reading
  • Amy C Cording, Nicolas Shiaelis, Stavroula Petridi, Chad A. Middleton, Laurence G Wilson, Christopher J H Elliott
  • Psychology, Medicine
  • npj Parkinson's Disease
  • 2017 (First Published: 1 December 2017)
  • In a number of Drosophila models of genetic Parkinson’s disease (PD) flies climb more slowly than wild-type controls. However, this assay does not distinguish effects of PD-related genes on gravityContinue Reading
  • Samantha J. Hindle, Farinaz Afsari, +4 authors Christopher J H Elliott
  • Biology, Medicine
  • Human molecular genetics
  • 2013 (First Published: 1 June 2013)
  • Parkinson's disease (PD) is associated with loss of dopaminergic signalling, and affects not just movement, but also vision. As both mammalian and fly visual systems contain dopaminergic neurons, weContinue Reading