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A method is described for the dissociation of guinea pig lung and mesentery into their component cells. The method comprises incubation of the tissues with the enzyme pronase in Ca++- and Mg++-free saline followed by mechanical dispersion and yields on average 3–8% free mast cells. These cells are morphologically intact and viable. They retain an active(More)
Some cases of hemoblastosis with CNS-involvement were investigated by methods of light microscopy, cytochemistry and electronmicroscopy. The unique cell picture, as observed by light microscopy could not be proven by electronmicroscopic results. This fact was supported by comparative investigations of inflammation processes. Typical structures are described(More)
The cardiac muscle fibers in the trabeculae carneae of mice, rats, and rabbits show a special arrangement of densely interwoven myofibrils. They cross at various angles; however, a preferred orientation of the fibrils cannot be discerned. It is suggested that due to this arrangement the myocytes of trabeculae are not able to contract to the same extent as(More)
The long-term effects of an anabolic steroid (Dianabol) an the liver of motor-active mice was investigated. The pathologic changes occurring are due to cholestasis, peliosis hepatis, and diffuse hepatitis. It was assumed that a pathogenic relationship between cholestasis, peliosis, and cirrhosis exists. Neoplasms seldom occurred, but it was suggested that(More)