Ch Roussos

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There is increasing evidence that the release of S100B protein, which is an acknowledged marker of brain injury, is also induced by other causes including hemorrhagic shock. The aim of this study was to investigate the serum concentration of S100B in critically ill mechanically ventilated patients with various degrees of organ dysfunction but without(More)
OBJECTIVE To analyze the time course of serum protein S-100b in patients with traumatic brain injury deteriorating to brain death and to investigate the predictive value of initial S-100b levels in relation to clinical and radiologic measures of injury severity with regard to brain death. METHODS Forty-seven patients who sustained severe head injury were(More)
OBJECTIVE To investigate risk factors of critical illness polyneuromyopathy (CIPM) in a general multidisciplinary intensive care unit (ICU). PATIENTS AND METHODS Prospective observational study in a 28-bed university multidisciplinary ICU. Four hundred and seventy-four (323 M/151 F, age 55 +/- 19) consecutive patients were prospectively evaluated. All(More)
It has been shown that expiratory muscle contraction leads to an overestimation of intrinsic positive end-expiratory pressure (PEEPi). To quantify this overestimation, we compared PEEPi, measured during spontaneous breathing (SB) by the end-expiratory airway occlusion technique (PEEPi,occl) with static PEEPi (PEEPi,st). PEEPi,st was measured using(More)