Celia E. Dominguez

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The development of functional hypothalamic amenorrhea (FHA) in weight-stable, nonathletic women has long been thought to be psychogenic in origin. This study was designed to gain insight into the possibility that nutritional deficits and compensatory endocrine-metabolic adaptations contribute to the development and maintenance of FHA of the psychogenic(More)
BACKGROUND Epidemiologists often use menstrual cycle patterns as indicators of endocrine function in environmental and occupational studies, yet few studies have considered whether menstrual cycle characteristics are associated with fertility or pregnancy outcome. METHODS We prospectively studied 470 women to determine whether cycle length or bleed length(More)
OBJECTIVE This study was undertaken to prospectively assess subjective anorectal symptoms by questionnaire and to prospectively assess the integrity of the anal sphincter by physical and ultrasonographic examination in women with and without obstetric anal sphincter laceration. STUDY DESIGN Fifteen subjects who sustained obstetric anal sphincter(More)
OBJECTIVE To examine the effect of follicular fluid (FF) and peritoneal fluid (PF) from patients undergoing assisted reproductive technology procedures on endothelial barrier function. This was determined in vitro by measuring the permeability of filter-grown bovine aortic endothelial cell monolayers to a permeability marker. DESIGN Endothelial cells(More)
BACKGROUND The upward trend in industrial nations in the incidence of male genitourinary (GU) conditions may be attributed to increased exposure to endocrine disruptors. Polybrominated biphenyl (PBB), a brominated flame retardant, is one such suspected endocrine disruptor. OBJECTIVE We investigated the relationship between maternal serum levels of PBBs(More)
BACKGROUND Pregnancy within a noncommunicating rudimentary horn is a known complication of unicornuate uterus. The risk of rupture approximates 50%, most of which occur in the second trimester. CASE A rudimentary horn pregnancy was discovered at 8 weeks gestation. Medical termination was then performed with fetal intracardiac potassium chloride and(More)
We previously suggested that women with endometriosis have increased oxidative stress in the peritoneal cavity. To assess whether antioxidant supplementation would ameliorate endometriosis-associated symptoms, we performed a randomized, placebo-controlled trial of antioxidant vitamins (vitamins E and C) in women with pelvic pain and endometriosis.(More)
OBJECTIVE To assess the subjective cure rates in a group of women who had undergone delayed/secondary anal sphincteroplasty and in a subgroup of women to compare the integrity of the anal sphincteric complex as evaluated by physical examination and vaginal probe anal sonography with subjective cure rates of fecal incontinence. STUDY DESIGN The charts of(More)
OBJECTIVE This study was undertaken to provide evidence for the mode of action of RU486 on glycodelin produced in K562 cells. To show that histiocytes may be a source of glycodelin in leiomyoma. STUDY DESIGN With the use of K562, a leukemia cell line, the effect of lysophosphatidic acid (LPA), RU486, antioxidants, and ZK112,993 on glycodelin protein and(More)
OBJECTIVE We hypothesized that glycodelin stimulates vascular endothelial growth factor (VEGF) expression in response to oxidative stress. STUDY DESIGN EM42 (human endometrial epithelial cell line) and primary endometrial epithelial cells were subjected to oxidative stress with minimally oxidized low density lipoprotein (mLDL). Cells were also incubated(More)