OBJECTIVE Mental health and cardiovascular disease have been associated, whereas the temporal course and underlying mechanisms are still incompletely understood. Our aims were to examine the presence of subclinical atherosclerosis in subjects with depressive or anxiety disorder, also taking into account disorder characteristics (subtype, severity, duration,… (More)
BACKGROUND Arterial stiffness gains attention as a potential mechanism underlying the frequently found association between depression or anxiety and cardiovascular disease. However, observations regarding stiffness and psychopathology were often based on small samples. The current study aimed to examine whether subjects with a diagnosis of depressive or… (More)
BACKGROUND Depressive and anxiety disorders are highly overlapping, heterogeneous conditions that both have been associated with an increased risk of cardiovascular disease (CVD). Cognitive vulnerability traits for these disorders could help to specify what exactly drives CVD risk in depressed and anxious subjects. Our aim is to examine sensitivity to… (More)
Objectives: The partly modifiable risk factors, that constitute the metabolic syndrome (MetS), do not fully account for the associated functional and structural vascular abnormalities and increased cardiovascular disease risk. Cell-derived microparticles, which reflect ongoing cellular stress but also associate with cardiovascular disease, are elevated in… (More)
Background & aims: Liver fat associates with postprandial hypertriglyceridemia, thus potentially contributing to postprandial triglyceride-enrichment of HDL (HDL-TG), and subsequent HDL dysfunction and finally cardiovascular disease.