Cedric Meylan

Learn More
Protein transduction domains (PTDs) are used to enhance cellular uptake of drugs, proteins, polynucleotides or liposomes. In this study, functionalized Antennapedia (Antp, aa 43-58) and HIV Tat (aa 47-57) peptides were coupled to small unilamellar liposomes via thiol-maleimide linkage. Modified liposomes showed higher uptake into a panel of cell lines(More)
In 198 consecutive deliveries in a region holoendemic for malaria, 39.4% of the mothers had malarial parasitaemia. Cord blood parasitaemia was found in 43 cases (55% of infected mothers). The incidence of malaria decreased with increasing parity possibly related to age. Malaria is partly responsible of the low birthweights and of the genesis of pre-term and(More)
After 9 days of risperidone therapy (2-6 mg/day), a 24-year-old schizophrenic female patient developed a leucopenia with neutropenia < 1000/mm3. A few days after starting the neuroleptic treatment, she suffered from a cold, without fever. All immunological tests performed yielded negative results except for influenza B virus. The cessation of the(More)
  • 1