Cecilia Engström

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BACKGROUND & AIMS It is important to evaluate the long-term effects of therapies for gastroesophageal reflux disease (GERD). In a 12-year study, we compared the effects of therapy with omeprazole with those of antireflux surgery. METHODS This open, parallel group study included 310 patients with esophagitis enrolled from outpatient clinics in Nordic(More)
OBJECTIVE AND BACKGROUND We lack long-term data (>10 years) on the efficacy of antireflux surgery when evaluated within the framework of randomized clinical trials Hereby we report the outcome of a randomized trial comparing open total (I) and a Toupet posterior partial fundoplication (II) performed between 1983 and 1991. METHODS One hundred and(More)
The development of lower third molar anlage was investigated longitudinally and related to chronological age and to skeletal maturation stage as judged by the mineralization of epiphyses in the hand. Strong correlations were found between lower third molar development and both skeletal maturation and chronological age. These results indicate that lower(More)
BACKGROUND Self-assessment questionnaires which measure the functional and affective consequences of chronic obstructive pulmonary disease (COPD) give valuable information about the effects of the disease and may serve as important tools with which to evaluate treatment. METHODS A cross sectional comparative study was performed between patients with COPD(More)
The St George's Respiratory Questionnaire (SGRQ) was designed to measure quality of life (QoL) in obstructive pulmonary disease. Its reliability, validity and sensitivity have been demonstrated. The aim was to develop a Swedish version of the SGRQ and to confirm its scaling and clinical properties. The SGRQ was adapted for Swedish conditions following a(More)
The regulation of degradative activity such as phagocytosis and bone resorption in the periodontal region is greatly influenced by factors controlling general bone modeling. The purpose of this study was to determine if thyroxine has any influence on the occurrence of force-induced root resorption. Young male rats were divided into three groups: a group of(More)
BACKGROUND There are few reports of large patient cohorts with long-term follow-up after laparoscopic antireflux surgery. This study was undertaken to evaluate changes in surgical practice and outcomes for laparoscopic antireflux surgery over a 20-year period. METHODS A standardized questionnaire, prospectively applied annually, was used to determine(More)
BACKGROUND Total fundoplication is the most common antireflux operation and can be performed with or without division of the short gastric vessels. There seems to be no difference in short-term outcomes with either approach. The aim of the study was to determine whether there were the long-term differences (after 10 years). METHODS Ninety-nine patients(More)
OBJECTIVES Gastroesophageal reflux disease (GERD)-associated changes in esophageal histology have been reported mainly after short-term medical antireflux therapy, and few individual lesions have been examined. We report detailed histological findings from the LOTUS study, at baseline and at 1 and 3 years after laparoscopic antireflux surgery (LARS) or(More)
Although research has consistently demonstrated that chronic obstructive pulmonary disease (COPD) impairs health-related quality of life (HRQL), little agreement has been evidenced regarding the factors identified as contributing to impaired HRQL. The aim was to study such factors using well established generic and specific HRQL instruments. The patients(More)