Cecil H Rorabeck

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We demonstrate the direct involvement of increased collagenase activity in the cleavage of type II collagen in osteoarthritic human femoral condylar cartilage by developing and using antibodies reactive to carboxy-terminal (COL2-3/4C(short)) and amino-terminal (COL2-1/4N1) neoepitopes generated by cleavage of native human type II collagen by collagenase(More)
BACKGROUND Postoperative analgesia with the use of parenteral opioids or epidural analgesia can be associated with troublesome side effects. Good perioperative analgesia facilitates rehabilitation, improves patient satisfaction, and may reduce the hospital stay. We investigated the analgesic effect of locally injected drugs around a total knee prosthesis.(More)
Patellar resurfacing in total knee arthroplasty remains controversial. This study evaluates the results of resurfacing and nonresurfacing the patella in a randomized controlled, clinical trial at a minimum of 10 years followup. One hundred knees (90 patients) with osteoarthritis were enrolled in a prospective randomized clinical trial using a(More)
UNLABELLED Gender-specific total knee replacement design is a recent and debated topic. We determined the survivorship and clinical outcomes of a large primary total knee arthroplasty cohort, specifically assessing any differences between gender groups. A consecutive cohort of 3817 patients with 5279 primary total knee replacements (3100 female, 2179 male)(More)
In summary, if TKRs are to be performed in patients who are younger and more active than those who had the initial procedures in the 1970s and 1980s, better wear performance is imperative for long-term durability, especially if surgeons continue to consider the versatility associated with modular knee-replacement systems to be a necessity. At least with(More)
Fractures of the femur in the presence of a total knee arthroplasty may occur intraoperatively or postoperatively. Management of these fractures is often challenging because of a variety of factors, including those related to the fracture itself, and the quality of the bone, prosthesis, and patient. Treatment options include nonoperative methods, reduction(More)
As the total number of knee arthroplasties increase, the frequency with which periprosthetic fractures will be encountered can be expected to increase as well. The classification of these fractures is an important aspect in the development of an understanding of these problems. Adequate classification systems allow accurate communication between researchers(More)
The results of 106 high tibial valgus osteotomies in 85 patients were evaluated after a minimum 10-year followup to determine survivorship, complications, and risk factors associated with failure. Using Kaplan-Meier survivorship analysis, 73% of patients at 5 years, 51% of patients at 10 years, 39% at 15 years, and 30% at 20 years after high tibial(More)
In 99 patients, 107 knee replacements were revised in two centers by two surgeons using a single revision total knee arthroplasty system. A retrospective radiographic review of joint line position before and after revision total knee arthroplasty was made, and compared with the joint line position before primary knee arthroplasty. Prospectively collected(More)
One hundred sixty patients (mean age, 68 +/- 8 years) having primary total knee arthroplasty were assigned randomly to two rehabilitation programs: (1) clinic-based rehabilitation provided by outpatient physical therapists; or (2) home-based rehabilitation monitored by periodic telephone calls from a physical therapist. Both rehabilitation programs(More)